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Isosorbide dinitrate
English Name: 1,4:3,6-dianhydrosorbitol 2,5-dinitrate; sorbide nitrate; Isosobide dinitrate; 1,4:3,6-dianhydro-2,5-di-O-nitrohexitol; 1,4:3,6-dianhydro-2,5-di-O-nitro-D-glucitol
CAS: 87-33-2 isosorbide dinitrate
EINECS number: 201-740-9
Molecular formula: C6H8N2O8
Molecular weight: 236.1363
Category: vasodilator.
Appearance: white crystalline powder; odorless. Isosorbide dinitrate
Solubility: soluble in acetone or chloroform, slightly soluble in ethanol, slightly soluble in water.
Density: 1.65g/cm3
Melting point: 68 ℃ ~ 72 ℃
Boiling point: 365.9 ° C at 760 mmHg
Flash point: 186.6 ° C
Indication.
Long-term treatment of coronary heart disease angina pectoris; prevention; treatment of persistent angina after myocardial infarction; and digitalis glycosides or diuretics combined application, the treatment of chronic congestive heart failure; treatment of pulmonary arterial hypertension.
Functions and indications:
The same with nitroglycerin, can be used for the treatment of various types of angina pectoris of coronary heart disease and prevention of seizures. Intravenous injection can be used in the treatment of congestive heart failure, various types of hypertensive emergencies and operation of hypertension control. |
