上海伊卡生物技术有限公司专业批发各种苯并芘/苯并芘/Benzo[a]pyrene/3,4-Benzopyrene,≥96%
苯并芘/苯并芘/BaP/Benzo[a]pyrene/3,4-Benzopyrene,≥96% (HPLC)
产品编号:B0003
中文名称:苯并芘/苯并芘/BaP/Benzo[a]pyrene/3,4-Benzopyrene
英文名称:3,4-Benzpyrene
英文别名:Benzo[def]chrysene
CAS号:50-32-8
分子式:C20H12分子量:252.31
纯度:≥96% (HPLC)
EC号:200-028-5
MDL号:MFCD00003602
订货信息:
产品规格价格(RMB)
B0003-100MG 460
性能描述
assay ≥96% (HPLC)
bp 495 °C(lit.)
mp 177-180 °C(lit.)
Application
Benzo[a]pyrene (PAH), a polycyclic aromatic hydrocarbon pollutant, is used as a chemical carcinogen in experimental models of cancer. Carcinogenesis depends on it′s oxidation by CYP1A1 to benzo[a]pyrenediolepoxide?, that forms depurinating adducts with DNA that dissociate to form abasic lesions. Benzo[a]pyrene is a ligand for the arylhydrocarbon receptor (AhR), and some of its biological effects, including the induction of CYP1A1, appear to be mediated via activation of the AhR.
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